+ 44 (0) 1709 361 241 info@kirkstall.com

Why Quasi Vivo®?

Quasi Vivo® is an advanced interconnected cell culture flow system, specifically designed to provide a solution to the major problems academic and industry researchers encounter when using conventional in vitro systems and in vivo research.

Quasi Vivo logo

SIGNIFICANTLY IMPROVED HUMAN RELEVANCE

By introducing flow to the in vitro environment, Quasi Vivo® significantly increases the physiological relevance of your research, enabling you to generate more accurate models, greatly improving confidence in the validity of your results.

Significant benefits include:

  • Improved cell viability
  • Close control of multiple variables
  • Flexible and easy to use
  • Time and cost savings
  • Long term culture
Diclofencac IC50 Assay

ADAPTABILITY

The Quasi Vivo® system has 3 different chambers available, each of these have been designed to meet the needs of specific applications.

QV500 Logo

Allows for submerged cell culture, whilst the modular nature allows for interconnecting cell co-culture.

QV600 Logo

Compatible with commercially available transwells and inserts, giving users the ability to culture cells at the air liquid interface and create liquid/liquid barrier models.

QV900 Logo

Consists of 6 chambers on a standard multi-well plate footprint and is made from a material with little to no non-specific binding.

 FLEXIBILITY

Using a Lego like building block system allows you to have great flexibility when designing your experiment.

Chambers are connected by a dynamic flow of media, transported through the system in tubing attached to chambers.

Quasi Vivo® chambers can be linked in series, allowing for the setup of extensive co-culture models.

QV500 Chamber

EASE OF USE

When it came to designing the Quasi Vivo® system, as well as delivering significant scientific benefits we’ve also ensured the system is very user friendly.

That’s why we’ve used luer locks to connect chambers to tubing, ensuring all seals are secure and liquid tight, whilst also being very easy to use.

New users can expect to be fully operational with as little as 4 hours training.

OXYGEN CONCENTRATIONS

The Quasi Vivo® systems were designed to provide metabolically active cells with ideal oxygen concentrations.

Furthermore oxygen gradients within the chamber can be predicted using computer modelling software and adapted by using inserts to alter the depth of the chambers.

Quasi Vivo Oxygen Concentrations
Quasi Vivo Shear Stress

FLOW RATE & SHEAR STRESS

The flow rate of the media is easily adapted by changing the settings on your peristaltic pump to ensure that the media perfuses cells at the correct level.

The chamber geometry ensures low levels of shear stress are applied to cells within the chamber (similar to that of hepatocyte shear stress), whilst using relatively high flow rates as delivered by the pump.

Again your desired level of shear stress can be predicted using computer modelling software and adapted by using inserts to alter the depth of the chambers.

MEDIA COMPOSITION

The recirculating media reduces the need for frequent media changes by allowing the cells themselves to condition their own environment and maintain this for over several days.

This leads to reduced perturbation of the system, giving you your weekends back!

Quasi Vivo 600 models

AND THERE’S MORE…

In addition to all of these benefits, Quasi Vivo also provides you with ultimate ease of use and flexibility;

  • Optimum scale for useful outputs
  • Scaffolds and Gels
  • Standard inserts and transwells
  • Fits in standard incubator
  • Powered by standard peristaltic pump
  • Works with any cell type

QUASI VIVO® USERS

The Quasi Vivo® system is commercially available and used for a variety of applications in academic and pharmaceutical laboratories.

Professor Jamie Davies

(University of Edinburgh, UK)

Professor of Experimental Anatomy and leader of a laboratory in Centre for Integrative Physiology.

Dr. Simon A. Whawell

(University of Sheffield, UK)

Reader in Oral Science & Director of Postgraduate Taught Courses Academic Unit of Oral & Maxillofacial Pathology School of Clinical Dentistry

Dr Miriam Dwek

(University of Westminster)

Reader in Biomedical Sciences, leader of the Cancer Research Group and Research Coordinator for the Department of Biomedical Sciences.

Quasi Vivo®, Commercially available and used in 70+ labs worldwide, getting started is easy and cost effective!

Contact Us

Kirkstall Ltd
3 Aspen Court
Centurion Business Park
Templeborough
Rotherham
S60 1FB

+ 44 (0) 1709 361 241
info@kirkstall.com

Products

QV500

QV600

QV900