Cell Culture Chamber
The QV600 chamber has been designed for surface cultures, such as skin, respiratory epithelium or whole corneas. Additionally, the use of transwells to create a double cavity chamber, ideal for the study of membranes and barrier models.
Is the QV600 system applicable to your project? Contact us to find out!
The QV600 provides a constant medium surface, positioned to allow the membrane on commercial inserts to sit at this height and provide cell cultures with a continuous perfusion of media as well as exposure to a controlled gaseous environment.
The QV600 chamber can also be fitted with an alternative insert to create a double cavity chamber ideal for the study of membranes and barrier models.
Users of the QV600 can expect to profit from a number of key benefits associate with the QV600 cell culture chambers;
- Continuous flow of medium across cell cultures
- Consistent ALI level within chambers – no risk of cells drying due to evaporation.
- Ports for control of gas within culture
- Simple fluid level control
- Sized for commercially available inserts
|Chamber width||15 mm internal|
|Chamber depth||33mm, minimum depth 12mm.|
Luers and reservoir bottle: Polypropylene
|Overall dimensions||23mm height x 37mm diameter|
|Diameter of tubing||Inlet: 1/16” ID
Outlet: 3/32” ID
|Volume of chamber||2ml running as ALI, 2x2ml with barrier insert.|
QV600 EVIDENCE AND VALIDATION
The QV600 chamber is currently being used by both academic and industrial labs worldwide, here’s a selection of the published papers that have used QV600 within their research.
A novel dual-flow bioreactor simulates increased fluorescein permeability in epithelial tissue barriers.
Authors: Giusti, S. et al., 2014.
Journal:Biotechnology Journal, 9, pp.1175–1184.
Commercially available and inserts can easily be fitted to the QV600 chambers, giving them great flexibility and a wide variety of applications;
- Respiratory System
- Gut model
- Blood-Brain Barrier
The QV600 starter kit contains everything you need to add flow to your experiments (except a peristaltic pump) – 3 chambers, tubing & reservoir bottle to form a complete circuit, holding trays for the complete system and a user guide.